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ProgesteroneProgesterone

Progesterone Oil for injection

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. It is used to treat missed menstrual periods or abnormal uterine bleeding caused by a hormone imbalance.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood vessel disease, blood clotting disorder, or suffered a stroke

  • breast, cervical or vaginal cancer

  • diabetes

  • heart disease

  • liver disease

  • recent abortion, miscarriage

  • vaginal bleeding

  • an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for injection into a muscle. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • bosentan

This medicine may also interact with the following medications:

  • barbiturate medicines for sleep or seizures

  • bexarotene

  • carbamazepine

  • ethotoin

  • ketoconazole

  • phenytoin

  • rifampin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breast tissue changes or discharge

  • breathing problems

  • changes in vaginal bleeding during your period or between your periods

  • changes in vision

  • depression

  • numbness or pain in the arm or leg

  • pain at site where injected

  • pain, swelling, warmth in the leg

  • problems with balance, talking, walking

  • sudden severe headache

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in emotions or moods

  • fluid retention and swelling

  • hair loss

  • increased in appetite

  • nausea

  • trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.


Progesterone Oral capsule

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. This medicine is used to prevent the overgrowth of the lining of the uterus in women who are taking estrogens for the symptoms of menopause. It is also used to treat secondary amenorrhea. This is when a woman stops getting menstrual periods due to low levels of progesterone.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • autoimmune disease like systemic lupus erythematosus (SLE)

  • blood vessel disease, blood clotting disorder, or suffered a stroke

  • breast, cervical or vaginal cancer

  • dementia

  • diabetes

  • kidney or liver disease

  • heart disease, high blood pressure or recent heart attack

  • high blood lipids or cholesterol

  • hysterectomy

  • recent miscarriage

  • tobacco smoker

  • vaginal bleeding

  • an unusual or allergic reaction to progesterone, peanuts, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • bosentan

This medicine may also interact with the following medications:

  • barbiturate medicines for sleep or seizures

  • bexarotene

  • carbamazepine

  • ethotoin

  • ketoconazole

  • phenytoin

  • rifampin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

This medicine can cause swelling, tenderness, or bleeding of the gums. Be careful when brushing and flossing teeth. See your dentist regularly for routine dental care.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breast tissue changes or discharge

  • changes in vaginal bleeding during your period or between your periods

  • depression

  • muscle or bone pain

  • numbness or pain in the arm or leg

  • pain in the chest, groin or leg

  • seizures or tremors

  • severe headache

  • stomach pain

  • sudden shortness of breath

  • unusually weak or tired

  • vision or speech problems

  • yellowing of skin or eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • acne

  • fluid retention and swelling

  • increased in appetite

  • mood changes, anxiety, depression, frustration, anger, or emotional outbursts

  • nausea, vomiting

  • sweating or hot flashes

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.


Progesterone Vaginal gel

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. This medicine is used to help women who are going through an Assisted Reproductive Technology (ART) treatment program to become pregnant. It is also used to treat secondary amenorrhea. This is when a woman stops getting menstrual periods due to low levels of progesterone.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood vessel disease, blood clotting disorder, or suffered a stroke

  • breast, cervical or vaginal cancer

  • heart disease

  • kidney disease

  • liver disease

  • miscarriage or abortion

  • vaginal bleeding

  • an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for use in the vagina. Do not take by mouth. Follow the directions on the prescription label. Use the applicator exactly as directed. Do not use more often than prescribed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other vaginal products without asking your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

If your doctor or health care professional instructs you to use any other medicines in the vagina while you are using this medicine, you should separate the doses by at least 6 hours.

You may notice a white discharge of medicine while using this medicine. This is normal. If it becomes bothersome, contact your doctor or health care professional.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • abnormal vaginal bleeding

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breast tissue changes or discharge

  • changes in vision

  • chest pain

  • confusion, trouble speaking or understanding

  • dark urine

  • general ill feeling or flu-like symptoms

  • light-colored stools

  • loss of appetite, nausea

  • pain, swelling, warmth in the leg

  • right upper belly pain

  • severe headaches

  • shortness of breath

  • sudden numbness or weakness of the face, arm or leg

  • trouble walking, dizziness, loss of balance or coordination

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • depressed mood or mood swings

  • increased appetite

  • fluid retention and swelling

  • nausea, vomiting

  • stomach cramps or bloating

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.


Progesterone Vaginal insert

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. This medicine is used to help women who are going through an assisted reproductive technology (ART) treatment program to become pregnant.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood vessel disease, blood clotting disorder, or suffered a stroke

  • breast, cervical or vaginal cancer

  • heart disease

  • kidney disease

  • liver disease

  • miscarriage or abortion

  • vaginal bleeding

  • an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for vaginal use only. Do not take by mouth. Follow the directions on the prescription label. Wash your hands before and after use. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

  • carbamazepine

  • rifampin

Do not use any other vaginal products without asking your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for a regular check on your progress.

This medicine can cause swelling, tenderness, or bleeding of the gums. Be careful when brushing and flossing teeth. See your dentist regularly for routine dental care.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • abnormal vaginal bleeding

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breast tissue changes or discharge

  • changes in vision

  • chest pain

  • confusion, trouble speaking or understanding

  • dark urine

  • general ill feeling or flu-like symptoms

  • light-colored stools

  • loss of appetite

  • pain, swelling, warmth in the leg

  • right upper belly pain

  • severe headaches

  • shortness of breath

  • sudden numbness or weakness of the face, arm or leg

  • trouble walking, dizziness, loss of balance or coordination

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • depressed mood or mood swings

  • increased appetite

  • fluid retention and swelling

  • nausea, vomiting

  • stomach cramps or bloating

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.


Progesterone Vaginal suppository

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. This medicine is used to treat infertility and to prevent miscarriage in women with a condition called corpus luteum insufficiency. This medicine may also be used to prevent preterm delivery in some women. The suppositories are only available when compounded by your pharmacist.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood vessel disease, blood clotting disorder, or suffered a stroke

  • breast, cervical or vaginal cancer

  • heart disease

  • kidney disease

  • liver disease

  • miscarriage or abortion

  • vaginal bleeding

  • an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for vaginal use only. Do not take by mouth. Follow the directions on the prescription label. Wash your hands before and after use. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other vaginal products without asking your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

If your doctor or health care professional instructs you to use any other medicines in the vagina while you are using this medicine, you should separate the doses by at least 6 hours.

You may notice a white discharge of medicine while using this medicine. This is normal. If it becomes bothersome, contact your doctor or health care professional.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • abnormal vaginal bleeding

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breast tissue changes or discharge

  • changes in vision

  • chest pain

  • confusion

  • dark urine

  • general ill feeling or flu-like symptoms

  • light-colored stools

  • loss of appetite, nausea

  • pain, swelling, warmth in the leg

  • right upper belly pain

  • problems with balance, talking, walking

  • severe headaches

  • shortness of breath

  • sudden numbness or weakness of the face, arm or leg

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • depressed mood or mood swings

  • increased appetite

  • fluid retention and swelling

  • nausea, vomiting

  • stomach cramps or bloating

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Protect from light. Keep this medicine in the orginal container until ready to use. Throw away any unused medicine after the expiration date.


 

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