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Current Stem Cell Applications

Since 1988, doctors have been using cord blood in lifesaving treatments. Stem cell research holds so much promise that the number of diseases and injuries being treated is growing rapidly.

Leukemias , Lymphomas and other Blood Cancers

  • Acute Biphenotypic Leukemia†
  • Acute Lymphocytic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Undifferentiated Leukemia†
  • Adult T Cell Leukemia/Lymphoma
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Hodgkin's Lymphoma
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Multiple Myeloma
  • Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia
  • Non-Hodgkin's Lymphoma
  • Prolymphocytic Leukemia
  • Plasma Cell Leukemia
  • Waldenstrom's Macroglobulinemia

Other Cancers

  • Brain Tumors††
  • Ewing Sarcoma†
  • Neuroblastoma
  • Ovarian Cancer††
  • Renal Cell Carcinoma††
  • Rhabdomyosarcoma
  • Small-Cell Lung Cancer††
  • Testicular Cancer††
  • Thymoma (Thymic Carcinoma)

Bone Marrow Failure Disorders

  • Amegakaryocytosis
  • Aplastic Anemia (Severe)
  • Blackfan-Diamond Anemia
  • Congenital Cytopenia†
  • Congenital Dyserythropoietic Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Pure Red Cell Aplasia

Hemoglobinopathies

  • Beta Thalassemia Major
  • Sickle Cell Disease

Histiocytic Disorders

  • Familial Erythrophagocytic Lymphohistiocytosis
  • Hemophagocytosis
  • Langerhans' Cell Histiocytosis (Histiocytosis X)

Myelodysplastic/Myeloproliferative Disorders

  • Acute Myelofibrosis†
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)†
  • Amyloidosis
  • Chronic Myelomonocytic Leukemia (CMML)
  • Essential Thrombocythemia†
  • Polycythemia Vera†
  • Refractory Anemias (RA) including:
  • Refractory Anemia with Excess Blasts (RAEB)
  • Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
  • Refractory Anemia with Ringed Sideroblasts (RARS)

Inherited Metabolic Disorders

  • Adrenoleukodystrophy
  • Fucosidosis
  • Gaucher Disease†
  • Hunter Syndrome (MPS-II)
  • Hurler Syndrome (MPS-IH)
  • Krabbe Disease
  • Lesch-Nyhan Syndrome
  • Mannosidosis†
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Metachromatic Leukodystrophy
  • Mucolipidosis II (I-cell Disease)†
  • Neuronal Ceroid Lipofuscinosis (Batten Disease)†
  • Niemann-Pick Disease†
  • Sandhoff Disease†
  • Sanfilippo Syndrome (MPS-III)
  • Scheie Syndrome (MPS-IS)
  • Sly Syndrome (MPS-VII)
  • Tay Sachs†
  • Wolman Disease

Inherited Immune System Disorders

  • Chronic Granulomatous Disease
  • Congenital Neutropenia
  • Leukocyte Adhesion Deficiency
  • Severe Combined Immunodeficiencies (SCID) including:
  • Adenosine Deaminase Deficiency†
  • Bare Lymphocyte Syndrome
  • Chediak-Higashi Syndrome†
  • Kostmann Syndrome
  • Omenn Syndrome
  • Purine Nucleoside Phosphorylase Deficiency
  • Reticular Dysgenesis
  • Wiskott-Aldrich Syndrome
  • X-Linked Lymphoproliferative Disorder

Other Inherited Disorders

  • Cartilage-Hair Hypoplasia
  • Congenital Erythropoietic Porphyria (Gunther Disease)
  • DiGeorge Syndrome
  • Osteopetrosis

Other

  • Chronic Active Epstein Barr
  • Evans Syndrome
  • Multiple Sclerosis††
  • Rheumatoid Arthritis††
  • Systemic Lupus Erythematosus††
  • Thymic Dysplasia

Emerging Stem Cell Applications††

  • Brain Injury
  • Cerebral Palsy
  • Type 1 Diabetes
  • Heart Disease

This list from Cord Blood Registry includes some diseases that have been treated with bone marrow or peripheral blood stem cells but have not yet been treated with cord blood stem cells.

†Refer to clinicaltrials.gov for additional information.
††Not routinely eligible for CBR's Designated Transplant Program®
Source: Medical literature and clinicaltrials.gov.